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2i5e

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[[Image:2i5e.gif|left|200px]]<br /><applet load="2i5e" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2i5e, resolution 2.10&Aring;" />
 
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'''Crystal Structure of a Protein of Unknown Function MM2497 from Methanosarcina mazei Go1, Probable Nucleotidyltransferase'''<br />
 
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==About this Structure==
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==Crystal Structure of a Protein of Unknown Function MM2497 from Methanosarcina mazei Go1, Probable Nucleotidyltransferase==
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2I5E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei] with <scene name='pdbligand=TRS:'>TRS</scene> and <scene name='pdbligand=PEG:'>PEG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I5E OCA].
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<StructureSection load='2i5e' size='340' side='right'caption='[[2i5e]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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[[Category: Methanosarcina mazei]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2i5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Metma Metma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I5E FirstGlance]. <br>
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[[Category: Clancy, S.]]
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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[[Category: Du, J.]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[Category: Joachimiak, A.]]
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Methanosarcina mazei ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192952 METMA])</td></tr>
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i5e OCA], [https://pdbe.org/2i5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i5e RCSB], [https://www.ebi.ac.uk/pdbsum/2i5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i5e ProSAT], [https://www.topsan.org/Proteins/MCSG/2i5e TOPSAN]</span></td></tr>
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[[Category: Tan, K.]]
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</table>
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[[Category: PEG]]
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== Function ==
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[[Category: TRS]]
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[[https://www.uniprot.org/uniprot/COFC_METMA COFC_METMA]] Guanylyltransferase that catalyzes the activation of 2-phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.[HAMAP-Rule:MF_02114]
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[[Category: apc86122]]
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== Evolutionary Conservation ==
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[[Category: hypothetic protein]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: mcsg]]
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Check<jmol>
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[[Category: methanosarcina mazei go1]]
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<jmolCheckbox>
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[[Category: midwest center for structural genomics]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/2i5e_consurf.spt"</scriptWhenChecked>
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[[Category: protein structure initiative]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: psi-2]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: structural genomics]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i5e ConSurf].
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:49:11 2008''
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Metma]]
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[[Category: Clancy, S]]
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[[Category: Du, J]]
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[[Category: Joachimiak, A]]
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[[Category: Structural genomic]]
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[[Category: Tan, K]]
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[[Category: Apc86122]]
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[[Category: Hypothetic protein]]
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[[Category: Mcsg]]
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[[Category: Methanosarcina mazei go1]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Unknown function]]

Current revision

Crystal Structure of a Protein of Unknown Function MM2497 from Methanosarcina mazei Go1, Probable Nucleotidyltransferase

PDB ID 2i5e

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