4ld0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4ld0 is ON HOLD Authors: Gorecka, K. M., Komorowska, W., Nowotny, M. Description: Protein-DNA complex) |
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| - | '''Unreleased structure''' | ||
| - | + | ==T. thermophilus RuvC in complex with Holliday junction substrate== | |
| - | + | <StructureSection load='4ld0' size='340' side='right'caption='[[4ld0]], [[Resolution|resolution]] 3.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ld0]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LD0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LD0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.75Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ld0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ld0 OCA], [https://pdbe.org/4ld0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ld0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ld0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ld0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RUVC_THET8 RUVC_THET8] Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermus thermophilus HB8]] | ||
| + | [[Category: Gorecka KM]] | ||
| + | [[Category: Komorowska W]] | ||
| + | [[Category: Nowotny M]] | ||
Current revision
T. thermophilus RuvC in complex with Holliday junction substrate
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