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4ldq
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the Mediator of Rho Dependent Invasion== | |
| - | + | <StructureSection load='4ldq' size='340' side='right'caption='[[4ldq]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ldq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LDQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LDQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.496Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ldq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ldq OCA], [https://pdbe.org/4ldq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ldq RCSB], [https://www.ebi.ac.uk/pdbsum/4ldq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ldq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MTNA_HUMAN MTNA_HUMAN] Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.<ref>PMID:19620624</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Metzner SI]] | ||
| + | [[Category: Sousa MC]] | ||
| + | [[Category: Templeton PD]] | ||
Current revision
Crystal Structure of the Mediator of Rho Dependent Invasion
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