4lg9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "4lg9" [edit=sysop:move=sysop])
Current revision (16:18, 20 September 2023) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 4lg9 is ON HOLD
+
==Crystal structure of TBL1XR1 WD40 repeats==
-
 
+
<StructureSection load='4lg9' size='340' side='right'caption='[[4lg9]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
-
Authors: Xu, C., Tempel, W., He, H., Wu, X., Bountra, C., Arrowsmith, C. H., Edwards, A. M., Min, J., Structural Genomics Consortium (SGC)
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4lg9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LG9 FirstGlance]. <br>
-
Description: Crystal structure of TBL1XR1 WD40 repeats
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lg9 OCA], [https://pdbe.org/4lg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lg9 RCSB], [https://www.ebi.ac.uk/pdbsum/4lg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lg9 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TBL1R_HUMAN TBL1R_HUMAN] F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.<ref>PMID:14980219</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Arrowsmith CH]]
 +
[[Category: Bountra C]]
 +
[[Category: Edwards AM]]
 +
[[Category: He H]]
 +
[[Category: Min J]]
 +
[[Category: Seitova A]]
 +
[[Category: Tempel W]]
 +
[[Category: Wu X]]
 +
[[Category: Xu C]]

Current revision

Crystal structure of TBL1XR1 WD40 repeats

PDB ID 4lg9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4lg9"
Personal tools