4j7q

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{{STRUCTURE_4j7q| PDB=4j7q | SCENE= }}
 
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===Crystal structure of Saccharomyces cerevisiae Sfh3 complexed with phosphatidylinositol===
 
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{{ABSTRACT_PUBMED_23603387}}
 
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==Function==
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==Crystal structure of Saccharomyces cerevisiae Sfh3 complexed with phosphatidylinositol==
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[[http://www.uniprot.org/uniprot/PDR16_YEAST PDR16_YEAST]] Has phosphatidylinositol transfer activity. Involved in the regulation of the phospholipid composition of plasma- and endomembranes. Altering plasma membrane composition may provide a possible mechanism for multidrug resistance. Involved in the regulation of sterol biosynthesis. Contributes to efficient phospholipase D1 activation in the regulation of phospholipid turnover.<ref>PMID:9890948</ref> <ref>PMID:10848624</ref>
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<StructureSection load='4j7q' size='340' side='right'caption='[[4j7q]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4j7q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J7Q FirstGlance]. <br>
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[[4j7q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J7Q OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B7N:(1R)-2-{[(S)-HYDROXY{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL]OXY}-1-[(OCTADECANOYLOXY)METHYL]ETHYL+(9Z)-OCTADEC-9-ENOATE'>B7N</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j7q OCA], [https://pdbe.org/4j7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j7q RCSB], [https://www.ebi.ac.uk/pdbsum/4j7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j7q ProSAT]</span></td></tr>
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<ref group="xtra">PMID:023603387</ref><references group="xtra"/><references/>
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</table>
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[[Category: Saccharomyces cerevisiae s288c]]
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== Function ==
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[[Category: Im, Y J.]]
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[https://www.uniprot.org/uniprot/PDR16_YEAST PDR16_YEAST] Has phosphatidylinositol transfer activity. Involved in the regulation of the phospholipid composition of plasma- and endomembranes. Altering plasma membrane composition may provide a possible mechanism for multidrug resistance. Involved in the regulation of sterol biosynthesis. Contributes to efficient phospholipase D1 activation in the regulation of phospholipid turnover.<ref>PMID:9890948</ref> <ref>PMID:10848624</ref>
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[[Category: Yang, H.]]
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== References ==
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[[Category: Lipid transport]]
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<references/>
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[[Category: Phosphatidylinositol]]
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__TOC__
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[[Category: Sec14 scaffold]]
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Im YJ]]
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[[Category: Yang H]]

Current revision

Crystal structure of Saccharomyces cerevisiae Sfh3 complexed with phosphatidylinositol

PDB ID 4j7q

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