2i7p
From Proteopedia
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| - | [[Image:2i7p.jpg|left|200px]]<br /><applet load="2i7p" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2i7p, resolution 2.05Å" /> | ||
| - | '''Crystal structure of human PANK3 in complex with AcCoA'''<br /> | ||
| - | == | + | ==Crystal structure of human PANK3 in complex with AcCoA== |
| - | + | <StructureSection load='2i7p' size='340' side='right'caption='[[2i7p]], [[Resolution|resolution]] 2.05Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[2i7p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I7P FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i7p OCA], [https://pdbe.org/2i7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i7p RCSB], [https://www.ebi.ac.uk/pdbsum/2i7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i7p ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/PANK3_HUMAN PANK3_HUMAN] Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity). | |
| - | [ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i7/2i7p_consurf.spt"</scriptWhenChecked> |
| - | [[ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i7p ConSurf]. | |
| - | [ | + | <div style="clear:both"></div> |
| - | [[ | + | |
| - | + | ||
| - | + | ||
| - | + | ==See Also== | |
| + | *[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bochkarev A]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Finerty P]] | ||
| + | [[Category: Hong BS]] | ||
| + | [[Category: Loppnau P]] | ||
| + | [[Category: Park HW]] | ||
| + | [[Category: Shen L]] | ||
| + | [[Category: Sundstrom M]] | ||
| + | [[Category: Tempel W]] | ||
| + | [[Category: Wang L]] | ||
| + | [[Category: Weigelt J]] | ||
Current revision
Crystal structure of human PANK3 in complex with AcCoA
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Edwards AM | Finerty P | Hong BS | Loppnau P | Park HW | Shen L | Sundstrom M | Tempel W | Wang L | Weigelt J
