4ee1

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{{STRUCTURE_4ee1| PDB=4ee1 | SCENE= }}
 
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===The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese===
 
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{{ABSTRACT_PUBMED_22795082}}
 
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==Function==
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==The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese==
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[[http://www.uniprot.org/uniprot/PRIM_STAAU PRIM_STAAU]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis.
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<StructureSection load='4ee1' size='340' side='right'caption='[[4ee1]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4ee1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EE1 FirstGlance]. <br>
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[[4ee1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EE1 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ee1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ee1 OCA], [https://pdbe.org/4ee1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ee1 RCSB], [https://www.ebi.ac.uk/pdbsum/4ee1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ee1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DNAG_STAAU DNAG_STAAU] RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.[HAMAP-Rule:MF_00974]
==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:022795082</ref><references group="xtra"/><references/>
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[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Berger, J M.]]
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[[Category: Berger JM]]
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[[Category: Chu, C.]]
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[[Category: Chu C]]
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[[Category: Corn, J E.]]
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[[Category: Corn JE]]
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[[Category: Rymer, R U.]]
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[[Category: Rymer RU]]
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[[Category: Solorio, F A.]]
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[[Category: Solorio FA]]
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[[Category: Wang, J D.]]
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[[Category: Wang JD]]
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[[Category: Bacterial]]
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[[Category: Catalytic domain]]
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[[Category: Nucleoside polyphosphate]]
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[[Category: Nucleoside triphosphate]]
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[[Category: Nucleotide]]
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[[Category: Protein-ligand complex]]
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[[Category: Transferase]]
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Current revision

The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese

PDB ID 4ee1

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