4jne

{{STRUCTURE_4jne| PDB=4jne | SCENE= }}

===Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP===

{{ABSTRACT_PUBMED_23708608}}

==Function==

[[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]

==About this Structure==

[[4jne]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JNE OCA].

 

<ref group="xtra">PMID:023708608</ref><references group="xtra"/><references/>

[[Category: Escherichia coli k-12]]

[[Category: Hendrickson, W A.]]

[[Category: Le, K Q.]]

[[Category: Liu, Q.]]

[[Category: Qi, R.]]

[[Category: Sarbeng, E B.]]

[[Category: Vorvis, C.]]

[[Category: Wong, J L.]]

[[Category: Xu, H.]]

[[Category: Xu, X.]]

[[Category: Yang, J.]]

[[Category: Zhou, L.]]

[[Category: Dnak]]