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4lij
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4lij is ON HOLD Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology Description: Crystal structure of a far upstre...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution== | |
| - | + | <StructureSection load='4lij' size='340' side='right'caption='[[4lij]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4lij]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LIJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lij OCA], [https://pdbe.org/4lij PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lij RCSB], [https://www.ebi.ac.uk/pdbsum/4lij PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lij ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FUBP1_HUMAN FUBP1_HUMAN] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.<ref>PMID:8125259</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Partnership for T-Cell Biology]] | ||
Current revision
Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution
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