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4j93
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| - | {{STRUCTURE_4j93| PDB=4j93 | SCENE= }} | ||
| - | ===Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With Inhibitor BI-1=== | ||
| - | == | + | ==Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With Inhibitor BI-1== |
| - | [[http://www.uniprot.org/uniprot/Q79791_9HIV1 Q79791_9HIV1 | + | <StructureSection load='4j93' size='340' side='right'caption='[[4j93]], [[Resolution|resolution]] 1.74Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4j93]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J93 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0OE:4-{2-[5-(3-CHLOROPHENYL)-1H-PYRAZOL-4-YL]-1-[3-(1H-IMIDAZOL-1-YL)PROPYL]-1H-BENZIMIDAZOL-5-YL}BENZOIC+ACID'>0OE</scene>, <scene name='pdbligand=1JR:(4S)-3-PHENYL-4-(PYRIDIN-3-YL)-4,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-6(2H)-ONE'>1JR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j93 OCA], [https://pdbe.org/4j93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j93 RCSB], [https://www.ebi.ac.uk/pdbsum/4j93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j93 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q79791_9HIV1 Q79791_9HIV1] Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).[SAAS:SAAS000071_004_008806] Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).[SAAS:SAAS000071_004_011858] | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Gag polyprotein 3D structures|Gag polyprotein 3D structures]] |
| + | *[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Lemke CT]] |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With Inhibitor BI-1
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