2iir
From Proteopedia
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| - | [[Image:2iir.jpg|left|200px]]<br /><applet load="2iir" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2iir, resolution 3.300Å" /> | ||
| - | '''Acetate kinase from a hypothermophile Thermotoga maritima'''<br /> | ||
| - | == | + | ==Acetate kinase from a hypothermophile Thermotoga maritima== |
| - | + | <StructureSection load='2iir' size='340' side='right'caption='[[2iir]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [[Category: | + | <table><tr><td colspan='2'>[[2iir]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IIR FirstGlance]. <br> |
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iir OCA], [https://pdbe.org/2iir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iir RCSB], [https://www.ebi.ac.uk/pdbsum/2iir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iir ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACKA_THEMA ACKA_THEMA] Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Phosphorylates propionate (54%) in addition to acetate (100%). Uses GTP (100%), ITP (163%), UTP (56%), and CTP (21%) as phosphoryl donors in addition to ATP (100%).<ref>PMID:10074080</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iir_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iir ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
| - | [[Category: Hasson | + | [[Category: Hasson MS]] |
| - | [[Category: Mukhopadhyay | + | [[Category: Mukhopadhyay S]] |
| - | [[Category: Sanders | + | [[Category: Sanders DA]] |
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Current revision
Acetate kinase from a hypothermophile Thermotoga maritima
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