4ezz

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{{STRUCTURE_4ezz| PDB=4ezz | SCENE= }}
 
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===Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide ELPLVKI===
 
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{{ABSTRACT_PUBMED_23562829}}
 
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==Function==
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==Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide ELPLVKI==
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[[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
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<StructureSection load='4ezz' size='340' side='right'caption='[[4ezz]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ezz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EZZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ezz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ezz OCA], [https://pdbe.org/4ezz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ezz RCSB], [https://www.ebi.ac.uk/pdbsum/4ezz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ezz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
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==About this Structure==
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==See Also==
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[[4ezz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZZ OCA].
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:023562829</ref><references group="xtra"/><references/>
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[[Category: Escherichia coli K-12]]
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[[Category: Escherichia coli k-12]]
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[[Category: Large Structures]]
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[[Category: Straeter, N.]]
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[[Category: Straeter N]]
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[[Category: Zahn, M.]]
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[[Category: Zahn M]]
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[[Category: Chaperone]]
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[[Category: Peptide binding mode]]
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Current revision

Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide ELPLVKI

PDB ID 4ezz

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