4evf
From Proteopedia
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- | {{STRUCTURE_4evf| PDB=4evf | SCENE= }} | ||
- | ===Crystal structure of apo alpha-1 giardin=== | ||
- | {{ABSTRACT_PUBMED_22796298}} | ||
- | == | + | ==Crystal structure of apo alpha-1 giardin== |
- | [[4evf]] is a 1 chain structure with sequence from [ | + | <StructureSection load='4evf' size='340' side='right'caption='[[4evf]], [[Resolution|resolution]] 1.90Å' scene=''> |
- | + | == Structural highlights == | |
- | == | + | <table><tr><td colspan='2'>[[4evf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Giardia_intestinalis Giardia intestinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EVF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EVF FirstGlance]. <br> |
- | < | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4evf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4evf OCA], [https://pdbe.org/4evf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4evf RCSB], [https://www.ebi.ac.uk/pdbsum/4evf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4evf ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/GIA1_GIAIN GIA1_GIAIN] Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Giardia intestinalis]] | [[Category: Giardia intestinalis]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Hofmann A]] |
- | [[Category: | + | [[Category: Weeratunga S]] |
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Current revision
Crystal structure of apo alpha-1 giardin
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