4g2v

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{{STRUCTURE_4g2v| PDB=4g2v | SCENE= }}
 
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===Structure complex of LGN binding with FRMPD1===
 
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{{ABSTRACT_PUBMED_23318951}}
 
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==Function==
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==Structure complex of LGN binding with FRMPD1==
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[[http://www.uniprot.org/uniprot/GPSM2_MOUSE GPSM2_MOUSE]] Plays an important role in spindle pole orientation (By similarity). Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions. [[http://www.uniprot.org/uniprot/FRPD1_HUMAN FRPD1_HUMAN]] Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1.<ref>PMID:18566450</ref>
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<StructureSection load='4g2v' size='340' side='right'caption='[[4g2v]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4g2v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G2V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G2V FirstGlance]. <br>
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[[4g2v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G2V OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g2v OCA], [https://pdbe.org/4g2v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g2v RCSB], [https://www.ebi.ac.uk/pdbsum/4g2v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g2v ProSAT]</span></td></tr>
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<ref group="xtra">PMID:023318951</ref><references group="xtra"/><references/>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GPSM2_MOUSE GPSM2_MOUSE] Plays an important role in spindle pole orientation (By similarity). Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions.
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Pan, Z.]]
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[[Category: Pan Z]]
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[[Category: Shang, Y.]]
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[[Category: Shang Y]]
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[[Category: Wang, W.]]
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[[Category: Wang W]]
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[[Category: Wen, W.]]
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[[Category: Wen W]]
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[[Category: Zhang, M.]]
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[[Category: Zhang M]]
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[[Category: Cell polarity]]
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[[Category: Lgn]]
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[[Category: Protein binding]]
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[[Category: Tpr repeat]]
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Current revision

Structure complex of LGN binding with FRMPD1

PDB ID 4g2v

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