2rt9

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m (Protected "2rt9" [edit=sysop:move=sysop])
Current revision (07:06, 1 May 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 2rt9 is ON HOLD
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==Solution structure of a regulatory domain of meiosis inhibitor==
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<StructureSection load='2rt9' size='340' side='right'caption='[[2rt9]]' scene=''>
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Authors: Shoji, S., Muto, Y., Ikeda, M., He, F., Tsuda, K., Ohsawa, N., Akasaka, R., Terada, T., Wakiyama, M., Shirouzu, M., Yokoyama, S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2rt9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RT9 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rt9 OCA], [https://pdbe.org/2rt9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rt9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rt9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rt9 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FBX43_MOUSE FBX43_MOUSE] Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Akasaka R]]
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[[Category: He F]]
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[[Category: Ikeda M]]
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[[Category: Muto Y]]
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[[Category: Ohsawa N]]
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[[Category: Shirouzu M]]
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[[Category: Shoji S]]
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[[Category: Terada T]]
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[[Category: Tsuda K]]
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[[Category: Wakiyama M]]
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[[Category: Yokoyama S]]

Current revision

Solution structure of a regulatory domain of meiosis inhibitor

PDB ID 2rt9

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