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2imr
From Proteopedia
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| - | [[Image:2imr.gif|left|200px]]<br /><applet load="2imr" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2imr, resolution 1.78Å" /> | ||
| - | '''Crystal structure of amidohydrolase DR_0824 from Deinococcus radiodurans'''<br /> | ||
| - | == | + | ==Crystal structure of amidohydrolase DR_0824 from Deinococcus radiodurans== |
| - | + | <StructureSection load='2imr' size='340' side='right'caption='[[2imr]], [[Resolution|resolution]] 1.78Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2imr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IMR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2imr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2imr OCA], [https://pdbe.org/2imr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2imr RCSB], [https://www.ebi.ac.uk/pdbsum/2imr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2imr ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2imr TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MQNX_DEIRA MQNX_DEIRA] Catalyzes the deamination of aminodeoxyfutalosine (AFL) into futalosine (FL). To a lesser extent, can also deaminate 5'-deoxyadenosine, 5'-methylthioadenosine, 2'-deoxyadenosine, adenosine, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide (NECA), and S-adenosylhomocysteine.<ref>PMID:23972005</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/2imr_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2imr ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Deinococcus radiodurans]] | [[Category: Deinococcus radiodurans]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Burley | + | [[Category: Burley SK]] |
| - | [[Category: Eswaramoorthy | + | [[Category: Eswaramoorthy S]] |
| - | + | [[Category: Swaminathan S]] | |
| - | [[Category: Swaminathan | + | |
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Current revision
Crystal structure of amidohydrolase DR_0824 from Deinococcus radiodurans
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