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4klp

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Current revision (10:39, 4 September 2013) (edit) (undo)
(Redirecting to 4lvs)
 
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{{STRUCTURE_4klp| PDB=4klp | SCENE= }}
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#REDIRECT [[4lvs]] This PDB entry is obsolete and replaced by 4lvs
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===DNA polymerase beta mismatched substrate complex with Mn2+, 2.5 min===
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{{ABSTRACT_PUBMED_23827680}}
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==Function==
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[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
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==About this Structure==
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[[4klp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KLP OCA].
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==Reference==
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<ref group="xtra">PMID:023827680</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Beard, W A.]]
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[[Category: Freudenthal, B D.]]
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[[Category: Shock, D D.]]
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[[Category: Wilson, S H.]]
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[[Category: Dna polymerase]]
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[[Category: Lyase-dna complex]]
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[[Category: Transferase]]
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Current revision

  1. REDIRECT 4lvs This PDB entry is obsolete and replaced by 4lvs

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