4i6a

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{{STRUCTURE_4i6a| PDB=4i6a | SCENE= }}
 
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===3-hydroxy-3-methylglutaryl (HMG) Coenzyme A reductase from Pseudomonas mevalonii complexed with HMG-CoA===
 
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{{ABSTRACT_PUBMED_23802607}}
 
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==Function==
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==3-hydroxy-3-methylglutaryl (HMG) Coenzyme A reductase from Pseudomonas mevalonii complexed with HMG-CoA==
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[[http://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV]] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
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<StructureSection load='4i6a' size='340' side='right'caption='[[4i6a]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4i6a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I6A FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HMG:3-HYDROXY-3-METHYLGLUTARYL-COENZYME+A'>HMG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i6a OCA], [https://pdbe.org/4i6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i6a RCSB], [https://www.ebi.ac.uk/pdbsum/4i6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i6a ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
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==About this Structure==
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==See Also==
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[[4i6a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I6A OCA].
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*[[HMG-CoA Reductase 3D structures|HMG-CoA Reductase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:023802607</ref><references group="xtra"/><references/>
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[[Category: Large Structures]]
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[[Category: Hydroxymethylglutaryl-CoA reductase]]
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[[Category: Pseudomonas mevalonii]]
[[Category: Pseudomonas mevalonii]]
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[[Category: Critchelow, C J.]]
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[[Category: Burgner II JW]]
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[[Category: II, J W.Burgner.]]
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[[Category: Critchelow CJ]]
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[[Category: Min, J.]]
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[[Category: Min J]]
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[[Category: Rodwell, V W.]]
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[[Category: Rodwell VW]]
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[[Category: Schmidt, T.]]
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[[Category: Schmidt T]]
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[[Category: Stauffacher, C V.]]
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[[Category: Stauffacher CV]]
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[[Category: Steussy, C N.]]
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[[Category: Steussy CN]]
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[[Category: Wrensford, L V.]]
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[[Category: Wrensford LV]]
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[[Category: Oxidoreductase]]
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Current revision

3-hydroxy-3-methylglutaryl (HMG) Coenzyme A reductase from Pseudomonas mevalonii complexed with HMG-CoA

PDB ID 4i6a

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