This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4g5f

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:39, 14 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4g5f| PDB=4g5f | SCENE= }}
 
-
===Pantothenate synthetase in complex with racemate (2S)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID and (2R)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID===
 
-
==Function==
+
==Pantothenate synthetase in complex with racemate (2S)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID and (2R)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID==
-
[[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref>
+
<StructureSection load='4g5f' size='340' side='right'caption='[[4g5f]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4g5f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G5F FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0JD:(2S)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC+ACID'>0JD</scene>, <scene name='pdbligand=15N:(2R)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC+ACID'>15N</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g5f OCA], [https://pdbe.org/4g5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g5f RCSB], [https://www.ebi.ac.uk/pdbsum/4g5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g5f ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref>
-
==About this Structure==
+
==See Also==
-
[[4g5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G5F OCA].
+
*[[Pantothenate synthetase|Pantothenate synthetase]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<references group="xtra"/><references/>
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
-
[[Category: Pantoate--beta-alanine ligase]]
+
[[Category: Abell C]]
-
[[Category: Abell, C.]]
+
[[Category: Blundell TL]]
-
[[Category: Blundell, T L.]]
+
[[Category: Ciulli A]]
-
[[Category: Ciulli, A.]]
+
[[Category: Silvestre HL]]
-
[[Category: Silvestre, H L.]]
+
-
[[Category: Atp binding pantoate binding beta-alanine binding]]
+
-
[[Category: Ligase]]
+
-
[[Category: Ligase-ligase inhibitor complex]]
+

Current revision

Pantothenate synthetase in complex with racemate (2S)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID and (2R)-2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBOXYLIC ACID

PDB ID 4g5f

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools