4kx6

==Plasticity of the quinone-binding site of the complex II homolog quinol:fumarate reductase==

<StructureSection load='4kx6' size='340' side='right'caption='[[4kx6]], [[Resolution|resolution]] 2.95&Aring;' scene=''>

== Structural highlights ==

<table><tr><td colspan='2'>[[4kx6]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BW2952 Escherichia coli BW2952], [https://en.wikipedia.org/wiki/Escherichia_coli_DH1 Escherichia coli DH1] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KX6 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MQ7:MENAQUINONE-7'>MQ7</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kx6 OCA], [https://pdbe.org/4kx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kx6 RCSB], [https://www.ebi.ac.uk/pdbsum/4kx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kx6 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/FRDA_ECOLI FRDA_ECOLI] Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

[[Category: Escherichia coli BW2952]]

[[Category: Escherichia coli DH1]]

[[Category: Escherichia coli K-12]]

[[Category: Large Structures]]

[[Category: Cecchini G]]

[[Category: Iverson TM]]

[[Category: Kotlyar V]]

[[Category: Maklashina E]]

[[Category: Rajagukguk S]]

[[Category: Sarwar M]]

[[Category: Singh PK]]

[[Category: Tomasiak TM]]