4kx6

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{{STRUCTURE_4kx6| PDB=4kx6 | SCENE= }}
 
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===Plasticity of the quinone-binding site of the complex II homolog quinol:fumarate reductase===
 
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{{ABSTRACT_PUBMED_23836905}}
 
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==Function==
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==Plasticity of the quinone-binding site of the complex II homolog quinol:fumarate reductase==
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[[http://www.uniprot.org/uniprot/FRDD_ECOLI FRDD_ECOLI]] Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.[HAMAP-Rule:MF_00709] [[http://www.uniprot.org/uniprot/FRDA_ECOLI FRDA_ECOLI]] Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. [[http://www.uniprot.org/uniprot/C9QU46_ECOD1 C9QU46_ECOD1]] Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity).[HAMAP-Rule:MF_00708]
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<StructureSection load='4kx6' size='340' side='right'caption='[[4kx6]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4kx6]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BW2952 Escherichia coli BW2952], [https://en.wikipedia.org/wiki/Escherichia_coli_DH1 Escherichia coli DH1] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KX6 FirstGlance]. <br>
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[[4kx6]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bw2952 Escherichia coli bw2952], [http://en.wikipedia.org/wiki/Escherichia_coli_dh1 Escherichia coli dh1] and [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KX6 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MQ7:MENAQUINONE-7'>MQ7</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kx6 OCA], [https://pdbe.org/4kx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kx6 RCSB], [https://www.ebi.ac.uk/pdbsum/4kx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kx6 ProSAT]</span></td></tr>
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<ref group="xtra">PMID:023836905</ref><references group="xtra"/><references/>
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</table>
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[[Category: Escherichia coli bw2952]]
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== Function ==
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[[Category: Escherichia coli dh1]]
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[https://www.uniprot.org/uniprot/FRDA_ECOLI FRDA_ECOLI] Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
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[[Category: Escherichia coli k-12]]
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__TOC__
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[[Category: Succinate dehydrogenase]]
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</StructureSection>
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[[Category: Cecchini, G.]]
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[[Category: Escherichia coli BW2952]]
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[[Category: Iverson, T M.]]
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[[Category: Escherichia coli DH1]]
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[[Category: Kotlyar, V.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Maklashina, E.]]
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[[Category: Large Structures]]
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[[Category: Rajagukguk, S.]]
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[[Category: Cecchini G]]
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[[Category: Sarwar, M.]]
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[[Category: Iverson TM]]
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[[Category: Singh, P K.]]
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[[Category: Kotlyar V]]
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[[Category: Tomasiak, T M.]]
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[[Category: Maklashina E]]
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[[Category: Complex ii homolog]]
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[[Category: Rajagukguk S]]
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[[Category: Frdc-e29l]]
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[[Category: Sarwar M]]
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[[Category: Membrane protein]]
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[[Category: Singh PK]]
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[[Category: Oxidoreductase]]
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[[Category: Tomasiak TM]]

Current revision

Plasticity of the quinone-binding site of the complex II homolog quinol:fumarate reductase

PDB ID 4kx6

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