4jkr

{{Large structure}}

{{STRUCTURE_4jkr| PDB=4jkr | SCENE= }}

===Crystal Structure of E. coli RNA Polymerase in complex with ppGpp===

{{ABSTRACT_PUBMED_23623685}}

==Function==

[[http://www.uniprot.org/uniprot/C9QUL2_ECOD1 C9QUL2_ECOD1]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).[HAMAP-Rule:MF_00366][SAAS:SAAS012293_004_017283] [[http://www.uniprot.org/uniprot/C5A0S8_ECOBW C5A0S8_ECOBW]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[SAAS:SAAS012754_004_011999] [[http://www.uniprot.org/uniprot/C9QV90_ECOD1 C9QV90_ECOD1]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[HAMAP-Rule:MF_01321][RuleBase:RU000432] [[http://www.uniprot.org/uniprot/RPOD_ECOLI RPOD_ECOLI]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium.

==About this Structure==

[[4jkr]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bw2952 Escherichia coli bw2952], [http://en.wikipedia.org/wiki/Escherichia_coli_dh1 Escherichia coli dh1], [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12] and [http://en.wikipedia.org/wiki/Escherichia_coli_o104:h4_str._2009el-2071 Escherichia coli o104:h4 str. 2009el-2071]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JKR OCA].

 

<ref group="xtra">PMID:023623685</ref><references group="xtra"/><references/>

[[Category: Escherichia coli bw2952]]

[[Category: Escherichia coli dh1]]

[[Category: Escherichia coli k-12]]

[[Category: Escherichia coli o104:h4 str. 2009el-2071]]

[[Category: Steitz, T A.]]

[[Category: Wang, Y.]]

[[Category: Zuo, Y.]]

[[Category: Rna polymerase]]

[[Category: Transferase]]