4fsa
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_4fsa| PDB=4fsa | SCENE= }} | ||
| - | ===tRNA-Guanine Transglycosylase soaked with pyridyl-alkine-substituted lin-benzoguanine ligand=== | ||
| - | == | + | ==tRNA-Guanine Transglycosylase soaked with pyridyl-alkine-substituted lin-benzoguanine ligand== |
| - | [[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO | + | <StructureSection load='4fsa' size='340' side='right'caption='[[4fsa]], [[Resolution|resolution]] 1.62Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4fsa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zymomonas_mobilis_subsp._mobilis_ZM4_=_ATCC_31821 Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FSA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0V3:6-AMINO-2-(METHYLAMINO)-4-[2-({[TRANS-4-(PYRIDIN-3-YLETHYNYL)CYCLOHEXYL]METHYL}AMINO)ETHYL]-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE'>0V3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fsa OCA], [https://pdbe.org/4fsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fsa RCSB], [https://www.ebi.ac.uk/pdbsum/4fsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fsa ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168] | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[TRNA-guanine transglycosylase 3D structures|TRNA-guanine transglycosylase 3D structures]] |
| - | [[Category: Zymomonas mobilis subsp. mobilis | + | __TOC__ |
| - | [[Category: Immekus | + | </StructureSection> |
| - | [[Category: Klebe | + | [[Category: Large Structures]] |
| - | + | [[Category: Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]] | |
| - | + | [[Category: Immekus F]] | |
| - | + | [[Category: Klebe G]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
tRNA-Guanine Transglycosylase soaked with pyridyl-alkine-substituted lin-benzoguanine ligand
| |||||||||||
