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4g6w

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{{STRUCTURE_4g6w| PDB=4g6w | SCENE= }}
 
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===Human Thymidylate Synthase M190K with bound 4-Bromobenzene-1,2,3-triol===
 
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==Function==
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==Human Thymidylate Synthase M190K with bound 4-Bromobenzene-1,2,3-triol==
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[[http://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref>
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<StructureSection load='4g6w' size='340' side='right'caption='[[4g6w]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4g6w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G6W FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=PBX:4-BROMOBENZENE-1,2,3-TRIOL'>PBX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g6w OCA], [https://pdbe.org/4g6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g6w RCSB], [https://www.ebi.ac.uk/pdbsum/4g6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g6w ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref>
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==About this Structure==
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==See Also==
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[[4g6w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G6W OCA].
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*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Thymidylate synthase]]
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[[Category: Large Structures]]
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[[Category: Celeste, L R.]]
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[[Category: Celeste LR]]
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[[Category: Lebioda, L.]]
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[[Category: Lebioda L]]
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[[Category: Methyltransferase]]
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[[Category: Transferase]]
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Current revision

Human Thymidylate Synthase M190K with bound 4-Bromobenzene-1,2,3-triol

PDB ID 4g6w

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