4lc2

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{{STRUCTURE_4lc2| PDB=4lc2 | SCENE= }}
 
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===Crystal structure of the bromodomain of human BRPF1B===
 
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==Function==
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==Crystal structure of the bromodomain of human BRPF1B==
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[[http://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>
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<StructureSection load='4lc2' size='340' side='right'caption='[[4lc2]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lc2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LC2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lc2 OCA], [https://pdbe.org/4lc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lc2 RCSB], [https://www.ebi.ac.uk/pdbsum/4lc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lc2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>
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==About this Structure==
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==See Also==
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[[4lc2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LC2 OCA].
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*[[Peregrin|Peregrin]]
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== References ==
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==Reference==
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<references/>
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<references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bountra, C.]]
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[[Category: Arrowsmith CH]]
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[[Category: Delft, F von.]]
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[[Category: Bountra C]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards AM]]
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[[Category: Filippakopoulos, P.]]
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[[Category: Filippakopoulos P]]
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[[Category: Knapp, S.]]
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[[Category: Knapp S]]
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[[Category: Nunez-Alonso, G.]]
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[[Category: Nunez-Alonso G]]
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[[Category: Picaud, S.]]
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[[Category: Picaud S]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Savitsky P]]
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[[Category: Savitsky, P.]]
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[[Category: Tallant C]]
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[[Category: Tallant, C.]]
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[[Category: Von Delft F]]
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[[Category: Bromodomain and phd finger-containing protein 1]]
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[[Category: Dna binding protein]]
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[[Category: Protein br140]]
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[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
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Current revision

Crystal structure of the bromodomain of human BRPF1B

PDB ID 4lc2

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