4eu5
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- | {{STRUCTURE_4eu5| PDB=4eu5 | SCENE= }} | ||
- | ===Succinyl-CoA:acetate CoA-transferase (AarCH6) in complex with CoA=== | ||
- | {{ABSTRACT_PUBMED_23030530}} | ||
- | == | + | ==Succinyl-CoA:acetate CoA-transferase (AarCH6) in complex with CoA== |
- | [[4eu5]] is a 2 chain structure with sequence from [ | + | <StructureSection load='4eu5' size='340' side='right'caption='[[4eu5]], [[Resolution|resolution]] 1.74Å' scene=''> |
- | + | == Structural highlights == | |
- | == | + | <table><tr><td colspan='2'>[[4eu5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetobacter_aceti Acetobacter aceti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EU5 FirstGlance]. <br> |
- | < | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.743Å</td></tr> |
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eu5 OCA], [https://pdbe.org/4eu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eu5 RCSB], [https://www.ebi.ac.uk/pdbsum/4eu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eu5 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/SCACT_ACEAC SCACT_ACEAC] Utilizes succinyl-CoA to convert toxic acetate to acetyl-CoA and succinate. Required for growth on acetic acid and for resistance to high levels of acetic acid. Has also low activity with acetoacetate as substrate.<ref>PMID:18502856</ref> <ref>PMID:23030530</ref> <ref>PMID:18502856</ref> [REFERENCE:3] | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Acetobacter aceti]] | [[Category: Acetobacter aceti]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Kappock | + | [[Category: Kappock TJ]] |
- | [[Category: Mullins | + | [[Category: Mullins EA]] |
- | + |
Current revision
Succinyl-CoA:acetate CoA-transferase (AarCH6) in complex with CoA
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