4lug
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana== | |
| + | <StructureSection load='4lug' size='340' side='right'caption='[[4lug]], [[Resolution|resolution]] 1.93Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4lug]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LUG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [https://pdbe.org/4lug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [https://www.ebi.ac.uk/pdbsum/4lug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lug ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IPYR1_ARATH IPYR1_ARATH] Catalyzes the irreversible hydrolysis of pyrophosphate (PPi) to phosphate. The MgPPi(2-) complex binds to the enzyme only after a free Mg(2+) ion has bound (Ref.9). No activity with glycerol-3-phosphate, glucose-6-phosphate, p-nitrophenylphosphate, ADP, NADP(+), NAD(+),NADH, NADPH or phosphoribosyl pyrophosphate as substrates (Ref.9). Controls the equilibrium of gluconeogenic reactions in the heterotrophic growth phase of early seedling establishment. Determinates the rate of cytosolic glycolysis, providing carbon for seed storage lipid accumulation (PubMed:22566496).<ref>PMID:22566496</ref> [REFERENCE:9] | ||
| - | + | ==See Also== | |
| - | + | *[[Inorganic pyrophosphatase 3D structures|Inorganic pyrophosphatase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arabidopsis thaliana]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Grzechowiak M]] | ||
| + | [[Category: Jaskolski M]] | ||
| + | [[Category: Ruszkowski M]] | ||
| + | [[Category: Sikorski M]] | ||
Current revision
Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana
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