4ldq
From Proteopedia
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- | {{STRUCTURE_4ldq| PDB=4ldq | SCENE= }} | ||
- | ===Crystal Structure of the Mediator of Rho Dependent Invasion=== | ||
- | {{ABSTRACT_PUBMED_23859498}} | ||
- | == | + | ==Crystal Structure of the Mediator of Rho Dependent Invasion== |
- | [[ | + | <StructureSection load='4ldq' size='340' side='right'caption='[[4ldq]], [[Resolution|resolution]] 2.50Å' scene=''> |
- | + | == Structural highlights == | |
- | == | + | <table><tr><td colspan='2'>[[4ldq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LDQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LDQ FirstGlance]. <br> |
- | [[4ldq]] is a 2 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.496Å</td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ldq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ldq OCA], [https://pdbe.org/4ldq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ldq RCSB], [https://www.ebi.ac.uk/pdbsum/4ldq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ldq ProSAT]</span></td></tr> | |
- | == | + | </table> |
- | < | + | == Function == |
+ | [https://www.uniprot.org/uniprot/MTNA_HUMAN MTNA_HUMAN] Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.<ref>PMID:19620624</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Metzner | + | [[Category: Metzner SI]] |
- | [[Category: Sousa | + | [[Category: Sousa MC]] |
- | [[Category: Templeton | + | [[Category: Templeton PD]] |
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Current revision
Crystal Structure of the Mediator of Rho Dependent Invasion
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