4lsg
From Proteopedia
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| - | {{STRUCTURE_4lsg| PDB=4lsg | SCENE= }} | ||
| - | ===Structure of Mouse P-Glycoprotein=== | ||
| - | == | + | ==Structure of Mouse P-Glycoprotein== |
| - | [[ | + | <StructureSection load='4lsg' size='340' side='right'caption='[[4lsg]], [[Resolution|resolution]] 3.80Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4lsg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LSG FirstGlance]. <br> |
| - | [[4lsg]] is a 2 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lsg OCA], [https://pdbe.org/4lsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lsg RCSB], [https://www.ebi.ac.uk/pdbsum/4lsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lsg ProSAT]</span></td></tr> |
| - | < | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Chang G]] | |
| - | [[Category: Chang | + | [[Category: Szewczyk P]] |
| - | [[Category: Szewczyk | + | |
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Current revision
Structure of Mouse P-Glycoprotein
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