2j8a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:35, 9 May 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2j8a.jpg|left|200px]]<br /><applet load="2j8a" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2j8a, resolution 3.00&Aring;" />
 
-
'''X-RAY STRUCTURE OF THE N-TERMINUS RRM DOMAIN OF SET1'''<br />
 
-
==About this Structure==
+
==X-ray structure of the N-terminus RRM domain of Set1==
-
2J8A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Active as [http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J8A OCA].
+
<StructureSection load='2j8a' size='340' side='right'caption='[[2j8a]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-
[[Category: Histone-lysine N-methyltransferase]]
+
== Structural highlights ==
-
[[Category: Saccharomyces cerevisiae]]
+
<table><tr><td colspan='2'>[[2j8a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J8A FirstGlance]. <br>
-
[[Category: Single protein]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
[[Category: Chavez, S.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j8a OCA], [https://pdbe.org/2j8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j8a RCSB], [https://www.ebi.ac.uk/pdbsum/2j8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j8a ProSAT]</span></td></tr>
-
[[Category: Couprie, J.]]
+
</table>
-
[[Category: Dehe, P M.]]
+
== Function ==
-
[[Category: Geli, V.]]
+
[https://www.uniprot.org/uniprot/SET1_YEAST SET1_YEAST] Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.<ref>PMID:11742990</ref> <ref>PMID:11751634</ref> <ref>PMID:11752412</ref> <ref>PMID:11805083</ref> <ref>PMID:11818070</ref> <ref>PMID:12060701</ref> <ref>PMID:12353038</ref> <ref>PMID:12845608</ref> <ref>PMID:14636589</ref> <ref>PMID:15949446</ref> <ref>PMID:9398665</ref> <ref>PMID:9988274</ref>
-
[[Category: Guerois, R.]]
+
== Evolutionary Conservation ==
-
[[Category: Leulliot, N.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Luciano, P.]]
+
Check<jmol>
-
[[Category: Pamblanco, M.]]
+
<jmolCheckbox>
-
[[Category: Quevillon-Cheruel, S.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j8/2j8a_consurf.spt"</scriptWhenChecked>
-
[[Category: Rodriguez-Gil, A.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Salah, P.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Sollier, J.]]
+
</jmolCheckbox>
-
[[Category: Tilbeurgh, H Van.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j8a ConSurf].
-
[[Category: Tordera, V.]]
+
<div style="clear:both"></div>
-
[[Category: Tresaugues, L.]]
+
-
[[Category: Varlet, I.]]
+
-
[[Category: Zinn-Justin, S.]]
+
-
[[Category: chromosomal protein]]
+
-
[[Category: histone methyltransferase]]
+
-
[[Category: methyltransferase]]
+
-
[[Category: nuclear protein]]
+
-
[[Category: rrm fold]]
+
-
[[Category: telomere]]
+
-
[[Category: transferase]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:00:18 2008''
+
==See Also==
 +
*[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]]
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Saccharomyces cerevisiae]]
 +
[[Category: Chavez S]]
 +
[[Category: Couprie J]]
 +
[[Category: Dehe PM]]
 +
[[Category: Geli V]]
 +
[[Category: Guerois R]]
 +
[[Category: Leulliot N]]
 +
[[Category: Luciano P]]
 +
[[Category: Pamblanco M]]
 +
[[Category: Quevillon-Cheruel S]]
 +
[[Category: Rodriguez-Gil A]]
 +
[[Category: Salah P]]
 +
[[Category: Sollier J]]
 +
[[Category: Tordera V]]
 +
[[Category: Tresaugues L]]
 +
[[Category: Van Tilbeurgh H]]
 +
[[Category: Varlet I]]
 +
[[Category: Zinn-Justin S]]

Current revision

X-ray structure of the N-terminus RRM domain of Set1

PDB ID 2j8a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2j8a"
Personal tools