3w0s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:43, 20 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_3w0s| PDB=3w0s | SCENE= }}
 
-
===Crystal structure of aminoglycoside phosphotransferase APH(4)-Ia, ternary complex with AMP-PNP and hygromycin B===
 
-
{{ABSTRACT_PUBMED_23747390}}
 
-
==Function==
+
==Crystal structure of aminoglycoside phosphotransferase APH(4)-Ia, ternary complex with AMP-PNP and hygromycin B==
-
[[http://www.uniprot.org/uniprot/KHYB_ECOLX KHYB_ECOLX]] The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation. Only phosphorylates hygromycin and closely related compounds such as demethyl analogs and destomycin.
+
<StructureSection load='3w0s' size='340' side='right'caption='[[3w0s]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[3w0s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W0S FirstGlance]. <br>
-
[[3w0s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W0S OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=HY0:HYGROMYCIN+B+VARIANT'>HY0</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
==Reference==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w0s OCA], [https://pdbe.org/3w0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w0s RCSB], [https://www.ebi.ac.uk/pdbsum/3w0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w0s ProSAT]</span></td></tr>
-
<ref group="xtra">PMID:023747390</ref><references group="xtra"/><references/>
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KHYB_ECOLX KHYB_ECOLX] The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation. Only phosphorylates hygromycin and closely related compounds such as demethyl analogs and destomycin.
 +
__TOC__
 +
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Hygromycin B 4-O-kinase]]
+
[[Category: Large Structures]]
-
[[Category: Fukano, K.]]
+
[[Category: Fukano K]]
-
[[Category: Hoshino, T.]]
+
[[Category: Hoshino T]]
-
[[Category: Iino, D.]]
+
[[Category: Iino D]]
-
[[Category: Nakamura, A.]]
+
[[Category: Nakamura A]]
-
[[Category: Ohsawa, K.]]
+
[[Category: Ohsawa K]]
-
[[Category: Sasaki, Y.]]
+
[[Category: Sasaki Y]]
-
[[Category: Takakura, Y.]]
+
[[Category: Takakura Y]]
-
[[Category: Yajima, S.]]
+
[[Category: Yajima S]]
-
[[Category: Phosphotransferase]]
+
-
[[Category: Transferase-antibiotic complex]]
+

Current revision

Crystal structure of aminoglycoside phosphotransferase APH(4)-Ia, ternary complex with AMP-PNP and hygromycin B

PDB ID 3w0s

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3w0s"
Personal tools