4g3i

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{{STRUCTURE_4g3i| PDB=4g3i | SCENE= }}
 
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===Crystal structure of Dpo4 in complex with DNA duplex===
 
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==Function==
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==Crystal structure of Dpo4 in complex with DNA duplex==
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[[http://www.uniprot.org/uniprot/DPO4_SULSO DPO4_SULSO]] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.[HAMAP-Rule:MF_01113]
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<StructureSection load='4g3i' size='340' side='right'caption='[[4g3i]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4g3i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G3I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g3i OCA], [https://pdbe.org/4g3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g3i RCSB], [https://www.ebi.ac.uk/pdbsum/4g3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g3i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.
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==About this Structure==
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==See Also==
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[[4g3i]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus_p2 Sulfolobus solfataricus p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G3I OCA].
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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[[Category: DNA-directed DNA polymerase]]
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__TOC__
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[[Category: Sulfolobus solfataricus p2]]
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</StructureSection>
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[[Category: Gan, J H.]]
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[[Category: Large Structures]]
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[[Category: Huang, Z.]]
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[[Category: Saccharolobus solfataricus P2]]
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[[Category: Yan, Y Y.]]
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[[Category: Synthetic construct]]
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[[Category: Dna synthesis]]
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[[Category: Gan JH]]
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[[Category: Transferase-dna complex]]
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[[Category: Huang Z]]
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[[Category: Yan YY]]

Current revision

Crystal structure of Dpo4 in complex with DNA duplex

PDB ID 4g3i

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