This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Signal recognition particle receptor

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:31, 20 November 2023) (edit) (undo)
 
(22 intermediate revisions not shown.)
Line 1: Line 1:
-
<Structure load='2fh5' size='400' frame='true' align='right' caption='Human SRPR α (grey) and β subunit (green) complex with GTP and Mg+2 (green) ion [[2fh5]]' scene= />
+
<StructureSection load='' size='350' side='right' scene='48/485587/Cv/1' caption='Human SRPR α (magenta) and β subunit (deepskyblue) complex with GTP and Mg+2 (green) ion [[2fh5]]'>
-
<!--
+
-
Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page.
+
-
Or use the four-green-boxes-button to insert scrollable text adjacent
+
-
to a Jmol applet. Check out the other buttons as well!
+
-
-->
+
-
'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called '''FtsY'''.
+
-
==3D structures of SRPR==
+
'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called '''FtsY'''.
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+
See also [[Intracellular receptors]]
-
[[1nrj]] – ySRPR α+β subunits + GTP – yeast<br />
+
*<scene name='48/485587/Cv/6'>GTP binding site</scene>. Water molecules are shown as red spheres.
-
[[2fh5]] - hSRPR α+β subunits + GTP – human<br />
+
*<scene name='48/485587/Cv/7'>Mg coordination site</scene>.
-
[[2ged]] - ySRPR β subunit (mutant)<br />
+
-
[[2go5]] - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - EM<br />
+
-
[[3dm9]], [[3dmd]], [[3e70 ]]– SRPR + GDP – ''Pyrococcus furiosus''
+
-
'''SRPR FtsY'''
+
==3D structures of signal recognition particle receptor==
-
[[1zu5]], [[1zu4]] – SRPR FtsY NG domain – ''Mycoplasma mycoides''<br />
+
[[Signal recognition particle receptor 3D structures]]
-
[[1vma]] – SRPR FtsY – ''Thermotoga maritima''<br />
+
-
[[2yhs]], [[2qy9]], [[1fts]] – EcSRPR FtsY NG domain – ''Escherichia coli''<br />
+
-
[[2q9a]] – EcSRPR FtsY <br />
+
-
[[2q9c]], [[2q9b]] – EcSRPR FtsY NG domain + GMPPNP<br />
+
-
[[2iyl]] – EcSRPR FtsY residues 20-303 + GDP<br />
+
-
[[2xxa]] - EcSRPR FtsY NG domain + signal recognition particle protein residues 1-433 (mutant) + 4.5SRNA<br />
+
-
[[3zn8]] - EcSRPR FtsY NG domain + signal recognition particle protein 54 NG domain + 4.5SRNA + dipeptidyl aminopeptidase B<br />
+
-
[[2j7p]], [[1rj9]], [[1okk]] – TaSRPR FtsY NG domain + signal recognition particle protein – ''Thermus aquaticus''<br />
+
-
[[2cnw]] – TaSRPR FtsY NG domain + signal recognition particle protein + GDP<br />
+
 +
</StructureSection>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Human SRPR α (magenta) and β subunit (deepskyblue) complex with GTP and Mg+2 (green) ion 2fh5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Signal_recognition_particle_receptor"
Personal tools