3ope

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{{STRUCTURE_3ope| PDB=3ope | SCENE= }}
 
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===Structural Basis of Auto-inhibitory mechanism of Histone methyltransferase===
 
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{{ABSTRACT_PUBMED_21239497}}
 
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==Function==
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==Structural Basis of Auto-inhibitory mechanism of Histone methyltransferase==
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[[http://www.uniprot.org/uniprot/ASH1L_HUMAN ASH1L_HUMAN]] Histone methyltransferase specifically methylating 'Lys-36' of histone H3 (H3K36me).<ref>PMID:21239497</ref>
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<StructureSection load='3ope' size='340' side='right'caption='[[3ope]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3ope]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OPE FirstGlance]. <br>
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[[3ope]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPE OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ope FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ope OCA], [https://pdbe.org/3ope PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ope RCSB], [https://www.ebi.ac.uk/pdbsum/3ope PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ope ProSAT]</span></td></tr>
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<ref group="xtra">PMID:021239497</ref><references group="xtra"/><references/>
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</table>
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[[Category: Histone-lysine N-methyltransferase]]
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== Function ==
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[https://www.uniprot.org/uniprot/ASH1L_HUMAN ASH1L_HUMAN] Histone methyltransferase specifically methylating 'Lys-36' of histone H3 (H3K36me).<ref>PMID:21239497</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: An, S.]]
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[[Category: Large Structures]]
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[[Category: Song, J.]]
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[[Category: An S]]
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[[Category: Methyltransferase]]
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[[Category: Song J]]
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[[Category: Nucleus]]
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[[Category: Set]]
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[[Category: Transferase]]
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Structural Basis of Auto-inhibitory mechanism of Histone methyltransferase

PDB ID 3ope

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