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4gi0

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{{STRUCTURE_4gi0| PDB=4gi0 | SCENE= }}
 
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===Crystal structure of CD23 lectin domain mutant E249A===
 
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{{ABSTRACT_PUBMED_23775083}}
 
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==Function==
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==Crystal structure of CD23 lectin domain mutant E249A==
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[[http://www.uniprot.org/uniprot/FCER2_HUMAN FCER2_HUMAN]] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
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<StructureSection load='4gi0' size='340' side='right'caption='[[4gi0]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gi0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GI0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gi0 OCA], [https://pdbe.org/4gi0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gi0 RCSB], [https://www.ebi.ac.uk/pdbsum/4gi0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gi0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FCER2_HUMAN FCER2_HUMAN] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
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==About this Structure==
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==See Also==
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[[4gi0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GI0 OCA].
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*[[CD23|CD23]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:023775083</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Dhaliwal, B.]]
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[[Category: Large Structures]]
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[[Category: Sutton, B J.]]
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[[Category: Dhaliwal B]]
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[[Category: Yuan, D.]]
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[[Category: Sutton BJ]]
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[[Category: Immune system]]
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[[Category: Yuan D]]
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[[Category: Receptor]]
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Current revision

Crystal structure of CD23 lectin domain mutant E249A

PDB ID 4gi0

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