4m2s
From Proteopedia
(Difference between revisions)
m (Protected "4m2s" [edit=sysop:move=sysop]) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR== | |
| - | + | <StructureSection load='4m2s' size='340' side='right'caption='[[4m2s]], [[Resolution|resolution]] 4.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4m2s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M2S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.4Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0JZ:(4R,11R,18R)-4,11,18-TRI(PROPAN-2-YL)-6,13,20-TRISELENA-3,10,17,22,23,24-HEXAAZATETRACYCLO[17.2.1.1~5,8~.1~12,15~]TETRACOSA-1(21),5(24),7,12(23),14,19(22)-HEXAENE-2,9,16-TRIONE'>0JZ</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m2s OCA], [https://pdbe.org/4m2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m2s RCSB], [https://www.ebi.ac.uk/pdbsum/4m2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m2s ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Aller SG]] | ||
| + | [[Category: Jaimes KF]] | ||
| + | [[Category: Li J]] | ||
Current revision
Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR
| |||||||||||
