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4m7f
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with bound ManNAc== | |
| - | + | <StructureSection load='4m7f' size='340' side='right'caption='[[4m7f]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4m7f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M7F FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BM3:2-(ACETYLAMINO)-2-DEOXY-ALPHA-D-MANNOPYRANOSE'>BM3</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m7f OCA], [https://pdbe.org/4m7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m7f RCSB], [https://www.ebi.ac.uk/pdbsum/4m7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m7f ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FBCD1_HUMAN FBCD1_HUMAN] Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components.<ref>PMID:19710473</ref> <ref>PMID:19892701</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Greenhough TJ]] | ||
| + | [[Category: Holmskov U]] | ||
| + | [[Category: Shrive AK]] | ||
Current revision
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with bound ManNAc
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