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3snf

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{{STRUCTURE_3snf| PDB=3snf | SCENE= }}
 
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===Onconase, atomic resolution crystal structure===
 
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{{ABSTRACT_PUBMED_21895975}}
 
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==Function==
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==Onconase, atomic resolution crystal structure==
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[[http://www.uniprot.org/uniprot/RNP30_RANPI RNP30_RANPI]] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA.
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<StructureSection load='3snf' size='340' side='right'caption='[[3snf]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3snf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_pipiens Lithobates pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SNF FirstGlance]. <br>
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[[3snf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rana_pipiens Rana pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SNF OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3snf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3snf OCA], [https://pdbe.org/3snf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3snf RCSB], [https://www.ebi.ac.uk/pdbsum/3snf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3snf ProSAT]</span></td></tr>
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<ref group="xtra">PMID:021895975</ref><references group="xtra"/><references/>
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</table>
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[[Category: Rana pipiens]]
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== Function ==
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[[Category: Acharya, K R.]]
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[https://www.uniprot.org/uniprot/RNP30_LITPI RNP30_LITPI] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA.
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[[Category: Holloway, D E.]]
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__TOC__
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[[Category: Shogen, K.]]
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</StructureSection>
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[[Category: Singh, U P.]]
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[[Category: Large Structures]]
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[[Category: Alpha/beta]]
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[[Category: Lithobates pipiens]]
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[[Category: Hydrolase]]
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[[Category: Acharya KR]]
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[[Category: Ribonuclease]]
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[[Category: Holloway DE]]
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[[Category: Shogen K]]
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[[Category: Singh UP]]

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Onconase, atomic resolution crystal structure

PDB ID 3snf

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