4g3t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:25, 1 March 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4g3t| PDB=4g3t | SCENE= }}
 
-
===Mycobacterium smegmatis DprE1 - hexagonal crystal form===
 
-
{{ABSTRACT_PUBMED_23184707}}
 
-
==About this Structure==
+
==Mycobacterium smegmatis DprE1 - hexagonal crystal form==
-
[[4g3t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G3T OCA].
+
<StructureSection load='4g3t' size='340' side='right'caption='[[4g3t]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==Reference==
+
<table><tr><td colspan='2'>[[4g3t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G3T FirstGlance]. <br>
-
<ref group="xtra">PMID:023184707</ref><references group="xtra"/><references/>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.346&#8491;</td></tr>
-
[[Category: Mycobacterium smegmatis]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g3t OCA], [https://pdbe.org/4g3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g3t RCSB], [https://www.ebi.ac.uk/pdbsum/4g3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g3t ProSAT]</span></td></tr>
-
[[Category: Jogl, G.]]
+
</table>
-
[[Category: Li, H.]]
+
== Function ==
-
[[Category: Oxidoreductase]]
+
[https://www.uniprot.org/uniprot/DPRE1_MYCS2 DPRE1_MYCS2] Component of the DprE1-DprE2 complex that catalyzes the 2-step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl-phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans (PubMed:22188377). DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX) (PubMed:22188377). The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'substrate channel' at the interface of DprE1-DprE2 complex (By similarity). Can also use farnesyl-phosphoryl-beta-D-ribofuranose (FPR) as substrate in vitro (PubMed:22188377, PubMed:22956199). Appears to be essential for the growth of M.smegmatis (PubMed:21346818).[UniProtKB:P9WJF1]<ref>PMID:21346818</ref> <ref>PMID:22188377</ref> <ref>PMID:22956199</ref>
-
[[Category: Vao superfamily]]
+
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Mycolicibacterium smegmatis]]
 +
[[Category: Jogl G]]
 +
[[Category: Li H]]

Current revision

Mycobacterium smegmatis DprE1 - hexagonal crystal form

PDB ID 4g3t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4g3t"
Personal tools