4ffb

{{STRUCTURE_4ffb| PDB=4ffb | SCENE= }}

===A TOG:alpha/beta-tubulin Complex Structure Reveals Conformation-Based Mechanisms For a Microtubule Polymerase===

{{ABSTRACT_PUBMED_22904013}}

==Function==

[[http://www.uniprot.org/uniprot/TBA1_YEAST TBA1_YEAST]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STU2_YEAST STU2_YEAST]] May play a role in the attachment, organization, and/or dynamics of microtubule ends at the spindle pole body. [[http://www.uniprot.org/uniprot/TBB_YEAST TBB_YEAST]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

 

[[4ffb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FFB OCA].

*[[Tubulin|Tubulin]]

 

<ref group="xtra">PMID:022904013</ref><references group="xtra"/><references/>

[[Category: Saccharomyces cerevisiae s288c]]

[[Category: Tubulin GTPase]]

[[Category: Ayaz, P.]]

[[Category: Brautigam, C A.]]

[[Category: Huddleston, P.]]

[[Category: Rice, L M.]]

[[Category: Ye, X.]]

[[Category: Tubulin fold]]