4ev4

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{{STRUCTURE_4ev4| PDB=4ev4 | SCENE= }}
 
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===Crystal structure of serratia fonticola carbapenemase SFC-1 E166A mutant with the acylenzyme intermediate of meropenem===
 
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{{ABSTRACT_PUBMED_23030300}}
 
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==About this Structure==
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==Crystal structure of serratia fonticola carbapenemase SFC-1 E166A mutant with the acylenzyme intermediate of meropenem==
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[[4ev4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Serratia_fonticola Serratia fonticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EV4 OCA].
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<StructureSection load='4ev4' size='340' side='right'caption='[[4ev4]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ev4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_fonticola Serratia fonticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EV4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EV4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HAR:N-OMEGA-HYDROXY-L-ARGININE'>HAR</scene>, <scene name='pdbligand=MER:(4R,5S)-3-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-5-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>MER</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ev4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ev4 OCA], [https://pdbe.org/4ev4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ev4 RCSB], [https://www.ebi.ac.uk/pdbsum/4ev4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ev4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q6JP75_SERFO Q6JP75_SERFO]
==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:023030300</ref><references group="xtra"/><references/>
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[[Category: Large Structures]]
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[[Category: Beta-lactamase]]
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[[Category: Serratia fonticola]]
[[Category: Serratia fonticola]]
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[[Category: Fonseca, F.]]
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[[Category: Fonseca F]]
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[[Category: Spencer, J.]]
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[[Category: Spencer J]]
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[[Category: Antibiotic resistance]]
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[[Category: Beta-lactamase complex]]
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[[Category: Carbapenemase]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-antibiotic complex]]
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Current revision

Crystal structure of serratia fonticola carbapenemase SFC-1 E166A mutant with the acylenzyme intermediate of meropenem

PDB ID 4ev4

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