4jfk
From Proteopedia
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| - | {{STRUCTURE_4jfk| PDB=4jfk | SCENE= }} | ||
| - | ===Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with (1S,6R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-10-[(2-oxo-2,3-dihydro-1,3-benzothiazol-6-yl)sulfonyl]-3,10-diazabicyclo[4.3.1]decan-2-one=== | ||
| - | {{ABSTRACT_PUBMED_23647266}} | ||
| - | == | + | ==Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with (1S,6R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-10-[(2-oxo-2,3-dihydro-1,3-benzothiazol-6-yl)sulfonyl]-3,10-diazabicyclo[4.3.1]decan-2-one== |
| - | [[http://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN | + | <StructureSection load='4jfk' size='340' side='right'caption='[[4jfk]], [[Resolution|resolution]] 1.15Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4jfk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JFK FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JFK:(1S,6R)-3-[2-(3,4-DIMETHOXYPHENOXY)ETHYL]-10-[(2-OXO-2,3-DIHYDRO-1,3-BENZOTHIAZOL-6-YL)SULFONYL]-3,10-DIAZABICYCLO[4.3.1]DECAN-2-ONE'>JFK</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jfk OCA], [https://pdbe.org/4jfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jfk RCSB], [https://www.ebi.ac.uk/pdbsum/4jfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jfk ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP. | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[FKBP 3D structures|FKBP 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Bracher | + | [[Category: Bracher A]] |
| - | [[Category: Fabian | + | [[Category: Fabian A]] |
| - | [[Category: Gopalakrishnan | + | [[Category: Gopalakrishnan R]] |
| - | [[Category: Hausch | + | [[Category: Hausch F]] |
| - | [[Category: Hoogeland | + | [[Category: Hoogeland B]] |
| - | [[Category: Kirschner | + | [[Category: Kirschner A]] |
| - | [[Category: Koch | + | [[Category: Koch U]] |
| - | [[Category: Kozany | + | [[Category: Kozany C]] |
| - | [[Category: Kress | + | [[Category: Kress C]] |
| - | [[Category: Wang | + | [[Category: Wang Y]] |
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Current revision
Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with (1S,6R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-10-[(2-oxo-2,3-dihydro-1,3-benzothiazol-6-yl)sulfonyl]-3,10-diazabicyclo[4.3.1]decan-2-one
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Categories: Homo sapiens | Large Structures | Bracher A | Fabian A | Gopalakrishnan R | Hausch F | Hoogeland B | Kirschner A | Koch U | Kozany C | Kress C | Wang Y
