2npo

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[[Image:2npo.gif|left|200px]]<br /><applet load="2npo" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2npo, resolution 2.20&Aring;" />
 
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'''Crystal structure of putative transferase from Campylobacter jejuni subsp. jejuni NCTC 11168'''<br />
 
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==About this Structure==
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==Crystal structure of putative transferase from Campylobacter jejuni subsp. jejuni NCTC 11168==
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2NPO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni Campylobacter jejuni]. Active as [http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPO OCA].
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<StructureSection load='2npo' size='340' side='right'caption='[[2npo]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2npo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni Campylobacter jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NPO FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2npo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2npo OCA], [https://pdbe.org/2npo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2npo RCSB], [https://www.ebi.ac.uk/pdbsum/2npo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2npo ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2npo TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PGLD_CAMJE PGLD_CAMJE] Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N'-diacetylbacillosamine in the N-linked protein glycosylation pathway.<ref>PMID:17087520</ref> <ref>PMID:19448740</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/np/2npo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2npo ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Campylobacter jejuni]]
[[Category: Campylobacter jejuni]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: UDP-N-acetylglucosamine diphosphorylase]]
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[[Category: Bera A]]
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[[Category: Bera, A.]]
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[[Category: Burley SK]]
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[[Category: Burley, S K.]]
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[[Category: Jin X]]
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[[Category: Jin, X.]]
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[[Category: Sauder JM]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Shapiro L]]
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[[Category: Sauder, J M.]]
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[[Category: Smith D]]
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[[Category: Shapiro, L.]]
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[[Category: Wasserman S]]
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[[Category: Smith, D.]]
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[[Category: Wasserman, S.]]
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[[Category: new york structural genomix research consortium]]
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[[Category: nysgxrc]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:09:28 2008''
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Current revision

Crystal structure of putative transferase from Campylobacter jejuni subsp. jejuni NCTC 11168

PDB ID 2npo

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