4m55
From Proteopedia
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| - | {{STRUCTURE_4m55| PDB=4m55 | SCENE= }} | ||
| - | ===Crystal structure of Human UDP-xylose synthase R236H substitution=== | ||
| - | == | + | ==Crystal structure of Human UDP-xylose synthase R236H substitution== |
| - | [[ | + | <StructureSection load='4m55' size='340' side='right'caption='[[4m55]], [[Resolution|resolution]] 2.86Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4m55]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M55 FirstGlance]. <br> |
| - | [[4m55]] is a 6 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m55 OCA], [https://pdbe.org/4m55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m55 RCSB], [https://www.ebi.ac.uk/pdbsum/4m55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m55 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UXS1_HUMAN UXS1_HUMAN] Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Polizzi | + | [[Category: Polizzi SJ]] |
| - | [[Category: Walsh | + | [[Category: Walsh Jr RM]] |
| - | [[Category: Wood | + | [[Category: Wood ZA]] |
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Current revision
Crystal structure of Human UDP-xylose synthase R236H substitution
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