2nyi
From Proteopedia
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| - | [[Image:2nyi.jpg|left|200px]]<br /><applet load="2nyi" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2nyi, resolution 1.80Å" /> | ||
| - | '''Crystal Structure of an Unknown Protein from Galdieria sulphuraria'''<br /> | ||
| - | == | + | ==Crystal Structure of an Unknown Protein from Galdieria sulphuraria== |
| - | + | <StructureSection load='2nyi' size='340' side='right'caption='[[2nyi]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[2nyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Galdieria_sulphuraria Galdieria sulphuraria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NYI FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nyi OCA], [https://pdbe.org/2nyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nyi RCSB], [https://www.ebi.ac.uk/pdbsum/2nyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nyi ProSAT], [https://www.topsan.org/Proteins/CESG/2nyi TOPSAN]</span></td></tr> |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/J3QW32_GALSU J3QW32_GALSU] |
| - | [[ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | [ | + | <jmolCheckbox> |
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ny/2nyi_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nyi ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The ACT domain is a structurally conserved small molecule binding domain which is mostly involved in amino acid and purine metabolism. Here, we report the crystal structure of a tandem ACT domain-containing protein (ACTP) from Galdieria sulphuraria. The two ACTP monomers in the asymmetric unit form a dimer with a non-crystallographic twofold axis in a domain-swapped manner, showing a horseshoe-like structure with a central crevice. This structure contributes to expand our knowledge on the structural diversity of ACT domain-containing proteins. Proteins 2012; (c) 2012 Wiley Periodicals, Inc. | ||
| - | + | Crystal structure of tandem ACT domain-containing protein ACTP from Galdieria sulphuraria.,Bitto E, Kim do J, Bingman CA, Kim HJ, Han BW, Phillips GN Jr Proteins. 2012 Aug;80(8):2105-9. doi: 10.1002/prot.24101. Epub 2012 Jun 7. PMID:22528523<ref>PMID:22528523</ref> | |
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 2nyi" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Galdieria sulphuraria]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bingman CA]] | ||
| + | [[Category: Bitto E]] | ||
| + | [[Category: McCoy JG]] | ||
| + | [[Category: Phillips Jr GN]] | ||
| + | [[Category: Wesenberg GE]] | ||
Current revision
Crystal Structure of an Unknown Protein from Galdieria sulphuraria
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