4m7e

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'''Unreleased structure'''
 
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The entry 4m7e is ON HOLD
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==Structural insight into BL-induced activation of the BRI1-BAK1 complex==
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<StructureSection load='4m7e' size='340' side='right'caption='[[4m7e]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
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Authors: Chai, J., Han, Z., Sun, Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4m7e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M7E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M7E FirstGlance]. <br>
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Description: Structural insight into BL-induced activation of the BRI1-BAK1 complex
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.602&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLD:BRASSINOLIDE'>BLD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m7e OCA], [https://pdbe.org/4m7e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m7e RCSB], [https://www.ebi.ac.uk/pdbsum/4m7e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m7e ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BRI1_ARATH BRI1_ARATH] Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Phosphorylates BRI1-associated receptor kinase 1 (BAK1), Transthyretin-Like protein (TTL) and SERK1 on 'Ser-299' and 'Thr-462' in vitro. May have a guanylyl cyclase activity.<ref>PMID:10557222</ref> <ref>PMID:10938344</ref> <ref>PMID:17138891</ref> <ref>PMID:17520012</ref> <ref>PMID:18694562</ref> <ref>PMID:19124768</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arabidopsis thaliana]]
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[[Category: Large Structures]]
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[[Category: Chai J]]
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[[Category: Han Z]]
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[[Category: Sun Y]]

Current revision

Structural insight into BL-induced activation of the BRI1-BAK1 complex

PDB ID 4m7e

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