2ly2

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{{STRUCTURE_2ly2| PDB=2ly2 | SCENE= }}
 
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===NMR structure of the second and third lotus domains of tudor domain-containing protein 7 (NMR ensemble overlay for Lotus #3)===
 
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==Function==
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==NMR structure of the second and third lotus domains of tudor domain-containing protein 7 (NMR ensemble overlay for Lotus #3)==
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[[http://www.uniprot.org/uniprot/TDRD7_MOUSE TDRD7_MOUSE]] Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.<ref>PMID:21436445</ref>
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<StructureSection load='2ly2' size='340' side='right'caption='[[2ly2]]' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[2ly2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LY2 FirstGlance]. <br>
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[[2ly2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY2 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ly2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ly2 OCA], [https://pdbe.org/2ly2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ly2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ly2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ly2 ProSAT]</span></td></tr>
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==Reference==
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</table>
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<references group="xtra"/><references/>
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== Function ==
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[https://www.uniprot.org/uniprot/TDRD7_MOUSE TDRD7_MOUSE] Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.<ref>PMID:21436445</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Botuyan, M.]]
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[[Category: Botuyan M]]
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[[Category: Cui, G.]]
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[[Category: Cui G]]
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[[Category: Mer, G.]]
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[[Category: Mer G]]
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[[Category: Germinal granule]]
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[[Category: Lotus domain]]
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[[Category: Ost-hth domain]]
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[[Category: Rna binding domain]]
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[[Category: Rna binding protein]]
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[[Category: Tdrd7]]
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Current revision

NMR structure of the second and third lotus domains of tudor domain-containing protein 7 (NMR ensemble overlay for Lotus #3)

PDB ID 2ly2

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