2mbf
From Proteopedia
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| - | {{STRUCTURE_2mbf| PDB=2mbf | SCENE= }} | ||
| - | ===Solution structure of the forkhead domain of Brugia malayi DAF-16a=== | ||
| - | == | + | ==Solution structure of the forkhead domain of Brugia malayi DAF-16a== |
| - | [[2mbf]] is a 1 chain structure with sequence from [ | + | <StructureSection load='2mbf' size='340' side='right'caption='[[2mbf]]' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2mbf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brugia_malayi Brugia malayi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MBF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mbf OCA], [https://pdbe.org/2mbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mbf RCSB], [https://www.ebi.ac.uk/pdbsum/2mbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mbf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Brugia malayi is a parasitic nematode that causes lymphatic filariasis in humans. Here the solution structure of the forkhead DNA binding domain of Brugia malayi DAF-16a, a putative ortholog of Caenorhabditis elegans DAF-16, is reported. It is believed to be the first structure of a forkhead or winged helix domain from an invertebrate. C. elegans DAF-16 is involved in the insulin/IGF-I signaling pathway and helps control metabolism, longevity, and development. Conservation of sequence and structure with human FOXO proteins suggests that B. malayi DAF-16a is a member of the FOXO family of forkhead proteins. Proteins 2014. (c) 2014 Wiley Periodicals, Inc. | ||
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| + | The solution structure of the forkhead box-O DNA binding domain of Brugia malayi DAF-16a.,Casper SK, Schoeller SJ, Zgoba DM, Phillips AJ, Morien TJ, Chaffee GR, Sackett PC, Peterson FC, Crossgrove K, Veldkamp CT Proteins. 2014 Oct 9. doi: 10.1002/prot.24701. PMID:25297652<ref>PMID:25297652</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 2mbf" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Brugia malayi]] | [[Category: Brugia malayi]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Casper SK]] |
| - | [[Category: | + | [[Category: Peterson FC]] |
| - | [[Category: | + | [[Category: Schoeller SJ]] |
| - | [[Category: | + | [[Category: Veldkamp CT]] |
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Current revision
Solution structure of the forkhead domain of Brugia malayi DAF-16a
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