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4c45
From Proteopedia
(Difference between revisions)
(New page: {{STRUCTURE_4c45| PDB=4c45 | SCENE= }} ===Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2)=== ==Function== [[http://www.uniprot.org/uniprot/PHS2_HUMAN PH...) |
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| - | {{STRUCTURE_4c45| PDB=4c45 | SCENE= }} | ||
| - | ===Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2)=== | ||
| - | == | + | ==Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2)== |
| - | [[ | + | <StructureSection load='4c45' size='340' side='right'caption='[[4c45]], [[Resolution|resolution]] 1.45Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4c45]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C45 FirstGlance]. <br> |
| - | [[4c45]] is a 1 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c45 OCA], [https://pdbe.org/4c45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c45 RCSB], [https://www.ebi.ac.uk/pdbsum/4c45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c45 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHS2_HUMAN PHS2_HUMAN] Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By similarity). Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Burgess-Brown | + | [[Category: Bountra C]] |
| - | [[Category: Canning | + | [[Category: Burgess-Brown N]] |
| - | + | [[Category: Canning P]] | |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Kiyani | + | [[Category: Kiyani W]] |
| - | [[Category: Kopec | + | [[Category: Kopec J]] |
| - | [[Category: Shrestha | + | [[Category: Shrestha L]] |
| - | [[Category: Vollmar | + | [[Category: Vollmar M]] |
| - | [[Category: Yue | + | [[Category: Yue WW]] |
| - | [[Category: | + | [[Category: Von Delft F]] |
Current revision
Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Burgess-Brown N | Canning P | Edwards A | Kiyani W | Kopec J | Shrestha L | Vollmar M | Yue WW | Von Delft F
