2o52

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:30, 30 August 2023) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2o52.gif|left|200px]]<br /><applet load="2o52" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2o52, resolution 2.200&Aring;" />
 
-
'''Crystal structure of human RAB4B in complex with GDP'''<br />
 
-
==About this Structure==
+
==Crystal structure of human RAB4B in complex with GDP==
-
2O52 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=GDP:'>GDP</scene>, <scene name='pdbligand=BME:'>BME</scene> and <scene name='pdbligand=UNX:'>UNX</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O52 OCA].
+
<StructureSection load='2o52' size='340' side='right'caption='[[2o52]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
[[Category: Homo sapiens]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2o52]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O52 FirstGlance]. <br>
-
[[Category: Arrowsmith, C H.]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
[[Category: Bochkarev, A.]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-
[[Category: Edwards, A M.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o52 OCA], [https://pdbe.org/2o52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o52 RCSB], [https://www.ebi.ac.uk/pdbsum/2o52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o52 ProSAT]</span></td></tr>
-
[[Category: Landry, R.]]
+
</table>
-
[[Category: Park, H.]]
+
== Function ==
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[https://www.uniprot.org/uniprot/RAB4B_HUMAN RAB4B_HUMAN] Protein transport. Probably involved in vesicular traffic (By similarity).
-
[[Category: Shen, Y.]]
+
== Evolutionary Conservation ==
-
[[Category: Sundstrom, M.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Tempel, W.]]
+
Check<jmol>
-
[[Category: Wang, J.]]
+
<jmolCheckbox>
-
[[Category: Weigelt, J.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o5/2o52_consurf.spt"</scriptWhenChecked>
-
[[Category: Zhu, H.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: BME]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: GDP]]
+
</jmolCheckbox>
-
[[Category: MG]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o52 ConSurf].
-
[[Category: UNX]]
+
<div style="clear:both"></div>
-
[[Category: g-protein]]
+
-
[[Category: gdp]]
+
-
[[Category: rab]]
+
-
[[Category: sgc]]
+
-
[[Category: structural genomics]]
+
-
[[Category: structural genomics consortium]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:14:32 2008''
+
==See Also==
 +
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Arrowsmith CH]]
 +
[[Category: Bochkarev A]]
 +
[[Category: Edwards AM]]
 +
[[Category: Landry R]]
 +
[[Category: Park H]]
 +
[[Category: Shen Y]]
 +
[[Category: Sundstrom M]]
 +
[[Category: Tempel W]]
 +
[[Category: Wang J]]
 +
[[Category: Weigelt J]]
 +
[[Category: Zhu H]]

Current revision

Crystal structure of human RAB4B in complex with GDP

PDB ID 2o52

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2o52"
Personal tools